Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model

Cutaneous squamous cell carcinomas are a common form of highly mutated keratinocyte skin cancers that are of particular concern in immunocompromised patients. Here we report on the efficacy of topically applied MS-275, a clinically used histone deacetylase inhibitor, for the treatment and management...

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Detalles Bibliográficos
Autores principales: Kalin, Jay H., Eroglu, Abdulkerim, Liu, Hua, Holtzclaw, W. David, Leigh, Irene, Proby, Charlotte M., Fahey, Jed W., Cole, Philip A., Dinkova-Kostova, Albena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415858/
https://www.ncbi.nlm.nih.gov/pubmed/30865688
http://dx.doi.org/10.1371/journal.pone.0213095

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