Towards a classification of stem cells

The characteristic properties of stem cells – notably their ability to self-renew and to differentiate – have meant that they have traditionally been viewed as distinct from most other types of cells. However, recent research has blurred the line between stem cells and other cells by showing that th...

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Detalles Bibliográficos
Autores principales: Laplane, Lucie, Solary, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415933/
https://www.ncbi.nlm.nih.gov/pubmed/30864951
http://dx.doi.org/10.7554/eLife.46563
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author Laplane, Lucie
Solary, Eric
author_facet Laplane, Lucie
Solary, Eric
author_sort Laplane, Lucie
collection PubMed
description The characteristic properties of stem cells – notably their ability to self-renew and to differentiate – have meant that they have traditionally been viewed as distinct from most other types of cells. However, recent research has blurred the line between stem cells and other cells by showing that the former display a range of behaviors in different tissues and at different stages of development. Here, we use the tools of metaphysics to describe a classification scheme for stem cells, and to highlight what their inherent diversity means for cancer treatment.
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spelling pubmed-64159332019-03-14 Towards a classification of stem cells Laplane, Lucie Solary, Eric eLife Stem Cells and Regenerative Medicine The characteristic properties of stem cells – notably their ability to self-renew and to differentiate – have meant that they have traditionally been viewed as distinct from most other types of cells. However, recent research has blurred the line between stem cells and other cells by showing that the former display a range of behaviors in different tissues and at different stages of development. Here, we use the tools of metaphysics to describe a classification scheme for stem cells, and to highlight what their inherent diversity means for cancer treatment. eLife Sciences Publications, Ltd 2019-03-13 /pmc/articles/PMC6415933/ /pubmed/30864951 http://dx.doi.org/10.7554/eLife.46563 Text en © 2019, Laplane and Solary http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Stem Cells and Regenerative Medicine
Laplane, Lucie
Solary, Eric
Towards a classification of stem cells
title Towards a classification of stem cells
title_full Towards a classification of stem cells
title_fullStr Towards a classification of stem cells
title_full_unstemmed Towards a classification of stem cells
title_short Towards a classification of stem cells
title_sort towards a classification of stem cells
topic Stem Cells and Regenerative Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415933/
https://www.ncbi.nlm.nih.gov/pubmed/30864951
http://dx.doi.org/10.7554/eLife.46563
work_keys_str_mv AT laplanelucie towardsaclassificationofstemcells
AT solaryeric towardsaclassificationofstemcells

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