Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells

The transcription factor BTB and CNC homology 1 (Bach1) is expressed in the embryos of mice, but whether Bach1 regulates the self-renewal and early differentiation of human embryonic stem cells (hESCs) is unknown. We report that the deubiquitinase ubiquitin-specific processing protease 7 (Usp7) is a...

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Detalles Bibliográficos
Autores principales: Wei, Xiangxiang, Guo, Jieyu, Li, Qinhan, Jia, Qianqian, Jing, Qing, Li, Yan, Zhou, Bin, Chen, Jiayu, Gao, Shaorong, Zhang, Xinyue, Jia, Mengping, Niu, Cong, Yang, Wenlong, Zhi, Xiuling, Wang, Xinhong, Yu, Dian, Bai, Lufeng, Wang, Lin, Na, Jie, Zou, Yunzeng, Zhang, Jianyi, Zhang, Shuning, Meng, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415956/
https://www.ncbi.nlm.nih.gov/pubmed/30891497
http://dx.doi.org/10.1126/sciadv.aau7887

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