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Tasmanian devils with contagious cancer exhibit a constricted T-cell repertoire diversity
The Tasmanian devil (Sarcophilus harrisii) is threatened by a contagious cancer, known as Devil Facial Tumour Disease (DFTD). A highly diverse T-cell receptor (TCR) repertoire is crucial for successful host defence against cancers. By investigating TCR beta chain diversity in devils of different age...
Autores principales: | Cheng, Yuanyuan, Makara, Mariano, Peel, Emma, Fox, Samantha, Papenfuss, Anthony T., Belov, Katherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416256/ https://www.ncbi.nlm.nih.gov/pubmed/30886908 http://dx.doi.org/10.1038/s42003-019-0342-5 |
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