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The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
Fibro/Adipogenic Progenitors (FAPs) define a stem cell population playing a pro-regenerative role after muscle damage. When removed from their natural niche, FAPs readily differentiate into adipocytes or fibroblasts. This digressive differentiation potential, which is kept under tight control in the...
Autores principales: | Reggio, Alessio, Spada, Filomena, Rosina, Marco, Massacci, Giorgia, Zuccotti, Alessandro, Fuoco, Claudia, Gargioli, Cesare, Castagnoli, Luisa, Cesareni, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416262/ https://www.ncbi.nlm.nih.gov/pubmed/30867438 http://dx.doi.org/10.1038/s41598-019-39538-y |
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