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Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products

Thiamine monophosphate kinase (ThiL) catalyzes the last step of thiamine pyrophosphate (TPP) synthesis, the ATP-dependent phosphorylation of thiamine monophosphate (TMP) to thiamine pyrophosphate. We solved the structure of ThiL from the human pathogen A. baumanii in complex with a pair of substrate...

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Detalles Bibliográficos
Autores principales:	Sullivan, Amy H., Dranow, David M., Horanyi, Peter S., Lorimer, Donald D., Edwards, Thomas E., Abendroth, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416309/ https://www.ncbi.nlm.nih.gov/pubmed/30867460 http://dx.doi.org/10.1038/s41598-019-40558-x

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