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Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

Here we report the transcriptional profile of human microglia, isolated from normal-appearing grey matter (GM) and white matter (WM) of multiple sclerosis (MS) and non-neurological control donors, to find possible early changes related to MS pathology. Microglia show a clear region-specific profile,...

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Detalles Bibliográficos
Autores principales:	van der Poel, Marlijn, Ulas, Thomas, Mizee, Mark R., Hsiao, Cheng-Chih, Miedema, Suzanne S. M., Adelia, Schuurman, Karianne G., Helder, Boy, Tas, Sander W., Schultze, Joachim L., Hamann, Jörg, Huitinga, Inge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416318/ https://www.ncbi.nlm.nih.gov/pubmed/30867424 http://dx.doi.org/10.1038/s41467-019-08976-7

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