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Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice
Here we have characterized the functional impairments resulting from conditional knockout of the ubiquitin-conjugating E2 enzyme (UBC13) in rodent cerebellar granule neurons, which greatly increases the parallel fiber presynaptic boutons and functional parallel fiber/Purkinje cell synapses. We repor...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416404/ https://www.ncbi.nlm.nih.gov/pubmed/30867488 http://dx.doi.org/10.1038/s41598-019-40714-3 |