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In vitro Drug Metabolism Investigation of 7-Ethoxycoumarin in Human, Monkey, Dog and Rat Hepatocytes by High Resolution LC-MS/MS

BACKGROUND: Recently, it has been an increasing concern on the bioactivation and adverse re-actions associated with consumption of herbal and nature products. 7-Ethoxycoumarin is one of coumarin family compounds, but little information is available regarding its potential reactive metabolites. METHO...

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Detalles Bibliográficos
Autores principales: Feng, Wan-Yong, Wen, Jenny, Stauber, Kathe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416465/
https://www.ncbi.nlm.nih.gov/pubmed/29669508
http://dx.doi.org/10.2174/1872312812666180418142056

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