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Numerical Model for Determining the Magnetic Loss of Magnetic Fluids
Magnetic fluid hyperthermia (MFH) is a medical treatment where the temperature in the tissue is increased locally by means of heated magnetic fluid in an alternating magnetic field. In recent years, it has been the subject of a lot of research in the field of Materials, as well as in the field of cl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416579/ https://www.ncbi.nlm.nih.gov/pubmed/30781473 http://dx.doi.org/10.3390/ma12040591 |
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author | Beković, Miloš Trbušić, Mislav Gyergyek, Sašo Trlep, Mladen Jesenik, Marko Szabo, Peter S. B. Hamler, Anton |
author_facet | Beković, Miloš Trbušić, Mislav Gyergyek, Sašo Trlep, Mladen Jesenik, Marko Szabo, Peter S. B. Hamler, Anton |
author_sort | Beković, Miloš |
collection | PubMed |
description | Magnetic fluid hyperthermia (MFH) is a medical treatment where the temperature in the tissue is increased locally by means of heated magnetic fluid in an alternating magnetic field. In recent years, it has been the subject of a lot of research in the field of Materials, as well as in the field of clinical testing on mice and rats. Magnetic fluid manufacturers aim to achieve three objectives; high heating capacity, biocompatibility and self-regulatory temperature effect. High heating power presents the conversion of magnetic field energy into temperature increase where it is challenging to achieve the desired therapeutic effects in terms of elevated temperature with the smallest possible amount of used material. In order to carry out the therapy, it is primarily necessary to create a fluid and perform calorimetric measurement for determining the Specific Absorption Rate (SAR) or heating power for given parameters of the magnetic field. The article presents a model based on a linear response theory for the calculation of magnetic losses and, consequently, the SAR parameters are based on the physical parameters of the liquid. The calculation model is also validated by calorimetric measurements for various amplitudes, frequencies and shapes of the magnetic field. Such a model can serve to help magnetic fluid developers in the development phase for an approximate assessment of the heating power. |
format | Online Article Text |
id | pubmed-6416579 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64165792019-03-29 Numerical Model for Determining the Magnetic Loss of Magnetic Fluids Beković, Miloš Trbušić, Mislav Gyergyek, Sašo Trlep, Mladen Jesenik, Marko Szabo, Peter S. B. Hamler, Anton Materials (Basel) Article Magnetic fluid hyperthermia (MFH) is a medical treatment where the temperature in the tissue is increased locally by means of heated magnetic fluid in an alternating magnetic field. In recent years, it has been the subject of a lot of research in the field of Materials, as well as in the field of clinical testing on mice and rats. Magnetic fluid manufacturers aim to achieve three objectives; high heating capacity, biocompatibility and self-regulatory temperature effect. High heating power presents the conversion of magnetic field energy into temperature increase where it is challenging to achieve the desired therapeutic effects in terms of elevated temperature with the smallest possible amount of used material. In order to carry out the therapy, it is primarily necessary to create a fluid and perform calorimetric measurement for determining the Specific Absorption Rate (SAR) or heating power for given parameters of the magnetic field. The article presents a model based on a linear response theory for the calculation of magnetic losses and, consequently, the SAR parameters are based on the physical parameters of the liquid. The calculation model is also validated by calorimetric measurements for various amplitudes, frequencies and shapes of the magnetic field. Such a model can serve to help magnetic fluid developers in the development phase for an approximate assessment of the heating power. MDPI 2019-02-16 /pmc/articles/PMC6416579/ /pubmed/30781473 http://dx.doi.org/10.3390/ma12040591 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Beković, Miloš Trbušić, Mislav Gyergyek, Sašo Trlep, Mladen Jesenik, Marko Szabo, Peter S. B. Hamler, Anton Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title | Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title_full | Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title_fullStr | Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title_full_unstemmed | Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title_short | Numerical Model for Determining the Magnetic Loss of Magnetic Fluids |
title_sort | numerical model for determining the magnetic loss of magnetic fluids |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416579/ https://www.ncbi.nlm.nih.gov/pubmed/30781473 http://dx.doi.org/10.3390/ma12040591 |
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