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The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings

Ursolic acid (UA) as a natural ursane-triterpenoid has rich pharmacological activities. We have found that it possesses aggregation properties and could self-assemble into organogels. Based on the aggregation property of ursolic acid in suitable solvents, its derivative appended with aromatic rings...

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Detalles Bibliográficos
Autores principales: Lu, Jinrong, Hu, Jinshan, Liang, Yinghua, Cui, Wenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416721/
https://www.ncbi.nlm.nih.gov/pubmed/30781693
http://dx.doi.org/10.3390/ma12040614
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author Lu, Jinrong
Hu, Jinshan
Liang, Yinghua
Cui, Wenquan
author_facet Lu, Jinrong
Hu, Jinshan
Liang, Yinghua
Cui, Wenquan
author_sort Lu, Jinrong
collection PubMed
description Ursolic acid (UA) as a natural ursane-triterpenoid has rich pharmacological activities. We have found that it possesses aggregation properties and could self-assemble into organogels. Based on the aggregation property of ursolic acid in suitable solvents, its derivative appended with aromatic rings by amide groups was synthesized. The property of self-assembly into organogel was studied in this paper. The results revealed that this derivative could form supramolecular gel in halogenated benzene and also gelate chloroform in the presence of toluene or p-xylene. By Fourier-transform infrared spectra (FT-IR) and variable temperature proton nuclear magnetic resonance ((1)H NMR), it was proved that intermolecular hydrogen bonding and π–π stacking interaction were the primary driving forces for the aggregation to form organogel.
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spelling pubmed-64167212019-03-29 The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings Lu, Jinrong Hu, Jinshan Liang, Yinghua Cui, Wenquan Materials (Basel) Article Ursolic acid (UA) as a natural ursane-triterpenoid has rich pharmacological activities. We have found that it possesses aggregation properties and could self-assemble into organogels. Based on the aggregation property of ursolic acid in suitable solvents, its derivative appended with aromatic rings by amide groups was synthesized. The property of self-assembly into organogel was studied in this paper. The results revealed that this derivative could form supramolecular gel in halogenated benzene and also gelate chloroform in the presence of toluene or p-xylene. By Fourier-transform infrared spectra (FT-IR) and variable temperature proton nuclear magnetic resonance ((1)H NMR), it was proved that intermolecular hydrogen bonding and π–π stacking interaction were the primary driving forces for the aggregation to form organogel. MDPI 2019-02-18 /pmc/articles/PMC6416721/ /pubmed/30781693 http://dx.doi.org/10.3390/ma12040614 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lu, Jinrong
Hu, Jinshan
Liang, Yinghua
Cui, Wenquan
The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title_full The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title_fullStr The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title_full_unstemmed The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title_short The Supramolecular Organogel Formed by Self-Assembly of Ursolic Acid Appended with Aromatic Rings
title_sort supramolecular organogel formed by self-assembly of ursolic acid appended with aromatic rings
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416721/
https://www.ncbi.nlm.nih.gov/pubmed/30781693
http://dx.doi.org/10.3390/ma12040614
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