Cargando…

Clinical aspects of TP53 gene inactivation in diffuse large B-cell lymphoma

BACKGROUND: The knowledge about specific mechanisms generating TP53 dysfunction in diffuse large B-cell lymphoma is limited. The aim of the current study was to comprehensively explore TP53 gene variability resulting from somatic mutations, promoter methylation, and allelic imbalance in tumorous tis...

Descripción completa

Detalles Bibliográficos
Autores principales: Voropaeva, Elena N., Pospelova, Tatyana I., Voevoda, Mikhail I., Maksimov, Vladimir N., Orlov, Yuriy L., Seregina, Olga B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416833/
https://www.ncbi.nlm.nih.gov/pubmed/30871527
http://dx.doi.org/10.1186/s12920-019-0484-9