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Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats
The highly virulent intracellular pathogen Francisella tularensis is a Gram-negative bacterium that has a wide host range, including humans, and is the causative agent of tularemia. To identify new therapeutic drug targets and vaccine candidates and investigate the genetic basis of Francisella virul...
Autores principales: | Ireland, Philip M., Bullifent, Helen L., Senior, Nicola J., Southern, Stephanie J., Yang, Zheng Rong, Ireland, Rachel E., Nelson, Michelle, Atkins, Helen S., Titball, Richard W., Scott, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416918/ https://www.ncbi.nlm.nih.gov/pubmed/30642993 http://dx.doi.org/10.1128/JB.00630-18 |
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