GRIBCG: a software for selection of sgRNAs in the design of balancer chromosomes

BACKGROUND: Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination. Recently, CRISPR/Cas9 genome editing has been shown capable of generating inversions similar to the chromosomal rearrangements present in balancer chromosomes. Extending the benefits of balance...

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Detalles Bibliográficos
Autores principales: Merritt, Brian B., Cheung, Lily S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416924/
https://www.ncbi.nlm.nih.gov/pubmed/30866794
http://dx.doi.org/10.1186/s12859-019-2712-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416924/
https://www.ncbi.nlm.nih.gov/pubmed/30866794
http://dx.doi.org/10.1186/s12859-019-2712-x

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