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GRIBCG: a software for selection of sgRNAs in the design of balancer chromosomes
BACKGROUND: Balancer chromosomes are tools used by fruit fly geneticists to prevent meiotic recombination. Recently, CRISPR/Cas9 genome editing has been shown capable of generating inversions similar to the chromosomal rearrangements present in balancer chromosomes. Extending the benefits of balance...
Autores principales: | Merritt, Brian B., Cheung, Lily S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416924/ https://www.ncbi.nlm.nih.gov/pubmed/30866794 http://dx.doi.org/10.1186/s12859-019-2712-x |
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