Cargando…

HR23B pathology preferentially co-localizes with p62, pTDP-43 and poly-GA in C9ORF72-linked frontotemporal dementia and amyotrophic lateral sclerosis

Human homologue of yeast UV excision repair protein Rad23b (HR23B) inclusions are found in a number of neurodegenerative diseases, including frontotemporal dementia (FTD), Huntington’s disease (HD), spinocerebellar ataxia type 3 and 7 (SCA3/7), fragile X associated tremor/ataxia syndrome (FXTAS) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riemslagh, Frederike W., Lans, Hannes, Seelaar, Harro, Severijnen, Lies-Anne W. F. M., Melhem, Shamiram, Vermeulen, Wim, Aronica, Eleonora, Pasterkamp, R. Jeroen, van Swieten, John C., Willemsen, Rob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416930/ https://www.ncbi.nlm.nih.gov/pubmed/30867060 http://dx.doi.org/10.1186/s40478-019-0694-6

Ejemplares similares

Atypical astroglial pTDP‐43 pathology in astroglial predominant tauopathy
por: Gelpi, Ellen, et al.
Publicado: (2021)

A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD
por: Hukema, Renate K, et al.
Publicado: (2014)

Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis
por: Tan, Rachel H., et al.
Publicado: (2023)

Retraction Note to: A new inducible transgenic mouse model for C9orf72-associated GGGGCC repeat expansion supports a gain-of-function mechanism in C9orf72-associated ALS and FTD
por: Hukema, Renate K., et al.
Publicado: (2016)

Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis
por: Schulthess, Ines, et al.
Publicado: (2016)

Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis
por: Cykowski, Matthew D., et al.
Publicado: (2018)

Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration
por: Seelaar, Harro, et al.
Publicado: (2009)

Eye Movement Deficits Are Consistent with a Staging Model of pTDP-43 Pathology in Amyotrophic Lateral Sclerosis
por: Gorges, Martin, et al.
Publicado: (2015)

Cortical iron accumulation in MAPT ‐ and C9orf 72‐associated frontotemporal lobar degeneration
por: Giannini, Lucia A. A., et al.
Publicado: (2023)

Novel TUBA4A Variant Associated With Familial Frontotemporal Dementia
por: Mol, Merel O., et al.
Publicado: (2021)

(18)F-Flortaucipir in TDP-43 associated frontotemporal dementia
por: Smith, R., et al.
Publicado: (2019)

Variation at GRN 3′-UTR rs5848 Is Not Associated with a Risk of Frontotemporal Lobar Degeneration in Dutch Population
por: Simón-Sánchez, Javier, et al.
Publicado: (2009)

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
por: Van Deerlin, Vivianna M., et al.
Publicado: (2010)

FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation
por: Chen, Dailu, et al.
Publicado: (2023)

pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with clinical phenotypic data
por: Pattle, Samuel B, et al.
Publicado: (2022)

Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration
por: Giannini, Lucia AA, et al.
Publicado: (2023)

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration
por: Urwin, Hazel, et al.
Publicado: (2010)

Frontotemporal Dementia: Correlations Between Psychiatric Symptoms and Pathology
por: Scarioni, Marta, et al.
Publicado: (2020)

Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology
por: Mol, Merel O., et al.
Publicado: (2022)

Mindfulness-Based Stress Reduction in Pre-symptomatic Genetic Frontotemporal Dementia: A Pilot Study
por: Poos, Jackie M., et al.
Publicado: (2022)

Molecular Pathways Involved in Frontotemporal Lobar Degeneration with TDP-43 Proteinopathy: What Can We Learn from Proteomics?
por: Mol, Merel O., et al.
Publicado: (2021)

Unfolded protein response activation in C9orf72 frontotemporal dementia is associated with dipeptide pathology and granulovacuolar degeneration in granule cells
por: Gami‐Patel, Priya, et al.
Publicado: (2020)

Psychiatric symptoms of frontotemporal dementia and subcortical (co-)pathology burden: new insights
por: Scarioni, Marta, et al.
Publicado: (2022)

TDP-43 pathology in the retina of patients with frontotemporal lobar degeneration
por: Dijkstra, Anke A., et al.
Publicado: (2023)

Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration
por: Giannini, Lucia A. A., et al.
Publicado: (2022)

Addition of the FTD Module to the Neuropsychiatric Inventory improves classification of frontotemporal dementia spectrum disorders
por: Jiskoot, Lize C., et al.
Publicado: (2023)

Correction to: Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration
por: Giannini, Lucia A. A., et al.
Publicado: (2023)

Clinical Value of Longitudinal Serum Neurofilament Light Chain in Prodromal Genetic Frontotemporal Dementia
por: Giannini, Lucia A.A., et al.
Publicado: (2023)

Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration
por: Yousef, Ahmed, et al.
Publicado: (2017)

TDP-43 and Inflammation: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
por: Bright, Fiona, et al.
Publicado: (2021)

TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration
por: Buciuc, Marina, et al.
Publicado: (2022)

Concurrent tau pathologies in frontotemporal lobar degeneration with TDP‐43 pathology
por: Koga, Shunsuke, et al.
Publicado: (2021)

Frontotemporal-TDP and LATE Neurocognitive Disorders: A Pathophysiological and Genetic Approach
por: Ortiz, Genaro Gabriel, et al.
Publicado: (2023)

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration
por: Foulds, Penelope, et al.
Publicado: (2008)

Longitudinal Brain Atrophy Rates in Presymptomatic Carriers of Genetic Frontotemporal Dementia
por: Poos, Jackie M., et al.
Publicado: (2022)

Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics
por: van der Ende, Emma L., et al.
Publicado: (2019)

In vivo staging of frontotemporal lobar degeneration TDP-43 type C pathology
por: Bocchetta, Martina, et al.
Publicado: (2020)

Cerebrospinal Fluid Biomarker Profile in TDP-43-Related Genetic Frontotemporal Dementia
por: Kapaki, Elisabeth, et al.
Publicado: (2022)

Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia
por: Miedema, Suzanne S. M., et al.
Publicado: (2022)

FRONTotemporal dementia Incidence European Research Study—FRONTIERS: Rationale and design
por: Borroni, Barbara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g35rjapieebct5diro3brqvvuc