Cargando…
Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study
BACKGROUND: Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC with risk factors, health variables and socioeconomic status in a community-based...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416949/ https://www.ncbi.nlm.nih.gov/pubmed/30866890 http://dx.doi.org/10.1186/s12890-019-0823-9 |
_version_ | 1783403462700040192 |
---|---|
author | Sakhamuri, Sateesh Lutchmansingh, Fallon Simeon, Donald Conyette, Liane Burney, Peter Seemungal, Terence |
author_facet | Sakhamuri, Sateesh Lutchmansingh, Fallon Simeon, Donald Conyette, Liane Burney, Peter Seemungal, Terence |
author_sort | Sakhamuri, Sateesh |
collection | PubMed |
description | BACKGROUND: Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC with risk factors, health variables and socioeconomic status in a community-based study of the Trinidad and Tobago population. METHODS: A cross-sectional survey was conducted using the Burden of Obstructive Lung Disease (BOLD) study protocol. Participants aged 40 years and above were selected using a two-stage stratified cluster sampling. Generalized linear models were used to examine associations between FVC and risk factors. RESULTS: Among the 1104 participants studied a lower post-bronchodilator FVC was independently associated with a large waist circumference (− 172 ml; 95% CI, − 66 to − 278), Indo-Caribbean ethnicity (− 180 ml; 95% CI, − 90 to − 269) and being underweight (− 185 ml; 95% CI, − 40 to − 330). A higher FVC was associated with smoking cannabis (+ 155 ml; 95% CI, + 27 to + 282). Separate analyses to examine associations with health variables indicated that participants with diabetes (p = 0∙041), history of breathlessness (p = 0∙007), and wheeze in the past 12 months (p = 0∙040) also exhibited lower post-bronchodilator FVC. CONCLUSION: These findings suggest that low FVC in this Caribbean population is associated with ethnicity, low body mass index (BMI), large waist circumference, chronic respiratory symptoms, and diabetes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12890-019-0823-9) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6416949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-64169492019-03-25 Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study Sakhamuri, Sateesh Lutchmansingh, Fallon Simeon, Donald Conyette, Liane Burney, Peter Seemungal, Terence BMC Pulm Med Research Article BACKGROUND: Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC with risk factors, health variables and socioeconomic status in a community-based study of the Trinidad and Tobago population. METHODS: A cross-sectional survey was conducted using the Burden of Obstructive Lung Disease (BOLD) study protocol. Participants aged 40 years and above were selected using a two-stage stratified cluster sampling. Generalized linear models were used to examine associations between FVC and risk factors. RESULTS: Among the 1104 participants studied a lower post-bronchodilator FVC was independently associated with a large waist circumference (− 172 ml; 95% CI, − 66 to − 278), Indo-Caribbean ethnicity (− 180 ml; 95% CI, − 90 to − 269) and being underweight (− 185 ml; 95% CI, − 40 to − 330). A higher FVC was associated with smoking cannabis (+ 155 ml; 95% CI, + 27 to + 282). Separate analyses to examine associations with health variables indicated that participants with diabetes (p = 0∙041), history of breathlessness (p = 0∙007), and wheeze in the past 12 months (p = 0∙040) also exhibited lower post-bronchodilator FVC. CONCLUSION: These findings suggest that low FVC in this Caribbean population is associated with ethnicity, low body mass index (BMI), large waist circumference, chronic respiratory symptoms, and diabetes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12890-019-0823-9) contains supplementary material, which is available to authorized users. BioMed Central 2019-03-14 /pmc/articles/PMC6416949/ /pubmed/30866890 http://dx.doi.org/10.1186/s12890-019-0823-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sakhamuri, Sateesh Lutchmansingh, Fallon Simeon, Donald Conyette, Liane Burney, Peter Seemungal, Terence Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title | Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title_full | Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title_fullStr | Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title_full_unstemmed | Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title_short | Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study |
title_sort | reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a caribbean population: a cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416949/ https://www.ncbi.nlm.nih.gov/pubmed/30866890 http://dx.doi.org/10.1186/s12890-019-0823-9 |
work_keys_str_mv | AT sakhamurisateesh reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy AT lutchmansinghfallon reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy AT simeondonald reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy AT conyetteliane reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy AT burneypeter reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy AT seemungalterence reducedforcedvitalcapacityisindependentlyassociatedwithethnicitymetabolicfactorsandrespiratorysymptomsinacaribbeanpopulationacrosssectionalstudy |