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Collagen density regulates the activity of tumor-infiltrating T cells

BACKGROUND: Tumor progression is accompanied by dramatic remodeling of the surrounding extracellular matrix leading to the formation of a tumor-specific ECM, which is often more collagen-rich and of increased stiffness. The altered ECM of the tumor supports cancer growth and metastasis, but it is un...

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Detalles Bibliográficos
Autores principales:	Kuczek, Dorota E., Larsen, Anne Mette H., Thorseth, Marie-Louise, Carretta, Marco, Kalvisa, Adrija, Siersbæk, Majken S., Simões, Ana Micaela C., Roslind, Anne, Engelholm, Lars H., Noessner, Elfriede, Donia, Marco, Svane, Inge Marie, Straten, Per thor, Grøntved, Lars, Madsen, Daniel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417085/ https://www.ncbi.nlm.nih.gov/pubmed/30867051 http://dx.doi.org/10.1186/s40425-019-0556-6

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