clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers

Measuring gene expression of tumor clones at single-cell resolution links functional consequences to somatic alterations. Without scalable methods to simultaneously assay DNA and RNA from the same single cell, parallel single-cell DNA and RNA measurements from independent cell populations must be ma...

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Detalles Bibliográficos
Autores principales: Campbell, Kieran R., Steif, Adi, Laks, Emma, Zahn, Hans, Lai, Daniel, McPherson, Andrew, Farahani, Hossein, Kabeer, Farhia, O’Flanagan, Ciara, Biele, Justina, Brimhall, Jazmine, Wang, Beixi, Walters, Pascale, Consortium, IMAXT, Bouchard-Côté, Alexandre, Aparicio, Samuel, Shah, Sohrab P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417140/
https://www.ncbi.nlm.nih.gov/pubmed/30866997
http://dx.doi.org/10.1186/s13059-019-1645-z

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