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Linear models enable powerful differential activity analysis in massively parallel reporter assays

BACKGROUND: Massively parallel reporter assays (MPRAs) have emerged as a popular means for understanding noncoding variation in a variety of conditions. While a large number of experiments have been described in the literature, analysis typically uses ad-hoc methods. There has been little attention...

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Detalles Bibliográficos
Autores principales: Myint, Leslie, Avramopoulos, Dimitrios G., Goff, Loyal A., Hansen, Kasper D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417258/
https://www.ncbi.nlm.nih.gov/pubmed/30866806
http://dx.doi.org/10.1186/s12864-019-5556-x

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