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“Physiological Dysregulation” as a Promising Measure of Robustness and Resilience in Studies of Aging and a New Indicator of Preclinical Disease
Recently suggested novel implementation of the statistical distance measure (D(M)) for evaluating “physiological dysregulation” (PD) in aging individuals (based on measuring deviations of multiple biomarkers from baseline or normal physiological states) allows reducing high-dimensional biomarker spa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417443/ https://www.ncbi.nlm.nih.gov/pubmed/29939206 http://dx.doi.org/10.1093/gerona/gly136 |