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“Physiological Dysregulation” as a Promising Measure of Robustness and Resilience in Studies of Aging and a New Indicator of Preclinical Disease

Recently suggested novel implementation of the statistical distance measure (D(M)) for evaluating “physiological dysregulation” (PD) in aging individuals (based on measuring deviations of multiple biomarkers from baseline or normal physiological states) allows reducing high-dimensional biomarker spa...

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Detalles Bibliográficos
Autores principales:	Arbeev, Konstantin G, Ukraintseva, Svetlana V, Bagley, Olivia, Zhbannikov, Ilya Y, Cohen, Alan A, Kulminski, Alexander M, Yashin, Anatoliy I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	The Journal of Gerontology: Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417443/ https://www.ncbi.nlm.nih.gov/pubmed/29939206 http://dx.doi.org/10.1093/gerona/gly136

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