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BIM deletion polymorphism predicts poor response to EGFR-TKIs in nonsmall cell lung cancer: An updated meta-analysis

BACKGROUND: A germline deletion in BIM (B cell lymphoma-2-like 11) gene has been shown to impair the apoptotic response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in vitro but its impact on response to EGFR-TKIs in patients of nonsmall cell lung cancer (NSCLC) remai...

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Detalles Bibliográficos
Autores principales: Su, Wenxia, Zhang, Xiaoyun, Cai, Xin, Peng, Meiyu, Wang, Fengbin, Wang, Yuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417537/
https://www.ncbi.nlm.nih.gov/pubmed/30855441
http://dx.doi.org/10.1097/MD.0000000000014568