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Mesenchymal stem cells inhibit T-cell function through conserved induction of cellular stress

The physiological role of mesenchymal stem cells (MSCs) is to provide a source of cells to replace mesenchymal-derivatives in stromal tissues with high cell turnover or following stromal tissue damage to elicit repair. Human MSCs have been shown to suppress in vitro T-cell responses via a number of...

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Detalles Bibliográficos
Autores principales: Laing, Adam G., Fanelli, Giorgia, Ramirez-Valdez, Andrei, Lechler, Robert I., Lombardi, Giovanna, Sharpe, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417714/
https://www.ncbi.nlm.nih.gov/pubmed/30870462
http://dx.doi.org/10.1371/journal.pone.0213170

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