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Inadequate BiP availability defines endoplasmic reticulum stress

How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy chain (μ(s)) thanks to the unfolded protein respons...

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Detalles Bibliográficos
Autores principales:	Vitale, Milena, Bakunts, Anush, Orsi, Andrea, Lari, Federica, Tadè, Laura, Danieli, Alberto, Rato, Claudia, Valetti, Caterina, Sitia, Roberto, Raimondi, Andrea, Christianson, John C, van Anken, Eelco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417858/ https://www.ncbi.nlm.nih.gov/pubmed/30869076 http://dx.doi.org/10.7554/eLife.41168

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