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Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature
Aggressive angiomyxoma (AAM) is an uncommon mesenchymal myxoid tumor that almost solely involves the soft tissues of the perineum and pelvis. An AAM originating from the liver is extremely rare. Herein, we present a case of a 45-year-old female with a large mass in the left lateral lobe of the liver...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418023/ https://www.ncbi.nlm.nih.gov/pubmed/30906733 http://dx.doi.org/10.3389/fonc.2019.00133 |
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author | Sun, Pi-Jiang Yu, Yan-Hua Cui, Xi-Jun |
author_facet | Sun, Pi-Jiang Yu, Yan-Hua Cui, Xi-Jun |
author_sort | Sun, Pi-Jiang |
collection | PubMed |
description | Aggressive angiomyxoma (AAM) is an uncommon mesenchymal myxoid tumor that almost solely involves the soft tissues of the perineum and pelvis. An AAM originating from the liver is extremely rare. Herein, we present a case of a 45-year-old female with a large mass in the left lateral lobe of the liver. She underwent a left lateral lobe hepatectomy. The histopathology of the resected specimen showed features that were characteristic of AAM. Immunohistochemical analysis of the neoplastic cells showed reactions to antibodies against CD34, smooth muscle actin (SMA), and Ki67 (2%) and showed no reactions to antibodies against Estrogen receptor (ER), C-keratin (CK), and Desmin. The patient was subsequently diagnosed with a primary AAM of the liver. This is the largest AAM of the liver that has been reported. We hereby report these findings and review the current literature. |
format | Online Article Text |
id | pubmed-6418023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64180232019-03-22 Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature Sun, Pi-Jiang Yu, Yan-Hua Cui, Xi-Jun Front Oncol Oncology Aggressive angiomyxoma (AAM) is an uncommon mesenchymal myxoid tumor that almost solely involves the soft tissues of the perineum and pelvis. An AAM originating from the liver is extremely rare. Herein, we present a case of a 45-year-old female with a large mass in the left lateral lobe of the liver. She underwent a left lateral lobe hepatectomy. The histopathology of the resected specimen showed features that were characteristic of AAM. Immunohistochemical analysis of the neoplastic cells showed reactions to antibodies against CD34, smooth muscle actin (SMA), and Ki67 (2%) and showed no reactions to antibodies against Estrogen receptor (ER), C-keratin (CK), and Desmin. The patient was subsequently diagnosed with a primary AAM of the liver. This is the largest AAM of the liver that has been reported. We hereby report these findings and review the current literature. Frontiers Media S.A. 2019-03-08 /pmc/articles/PMC6418023/ /pubmed/30906733 http://dx.doi.org/10.3389/fonc.2019.00133 Text en Copyright © 2019 Sun, Yu and Cui. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Sun, Pi-Jiang Yu, Yan-Hua Cui, Xi-Jun Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title | Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title_full | Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title_fullStr | Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title_full_unstemmed | Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title_short | Large Aggressive Angiomyxoma of the Liver: A Case Report and Brief Review of the Literature |
title_sort | large aggressive angiomyxoma of the liver: a case report and brief review of the literature |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418023/ https://www.ncbi.nlm.nih.gov/pubmed/30906733 http://dx.doi.org/10.3389/fonc.2019.00133 |
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