Identification of regulators of the myofibroblast phenotype of primary dermal fibroblasts from early diffuse systemic sclerosis patients

Systemic sclerosis (SSc or scleroderma) is an auto-immune disease characterized by skin fibrosis. While primary cells from patients are considered as a unique resource to better understand human disease biology, the effect of in vitro culture on these cells and their evaluation as a platform to iden...

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Detalles Bibliográficos
Autores principales: Chadli, Loubna, Sotthewes, Britt, Li, Kejie, Andersen, Stefan N., Cahir-McFarland, Ellen, Cheung, Marc, Cullen, Patrick, Dorjée, Annemarie, de Vries-Bouwstra, Jeska K., Huizinga, Tom W. J., Fischer, David F., DeGroot, Jeroen, Viney, Joanne L., Zheng, Timothy S., Aarbiou, Jamil, Gardet, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418101/
https://www.ncbi.nlm.nih.gov/pubmed/30872777
http://dx.doi.org/10.1038/s41598-019-41153-w

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