Memory and relatedness of transcriptional activity in mammalian cell lineages

Phenotypically identical mammalian cells often display considerable variability in transcript levels of individual genes. How transcriptional activity propagates in cell lineages, and how this varies across genes is poorly understood. Here we combine live-cell imaging of short-lived transcriptional...

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Detalles Bibliográficos
Autores principales: Phillips, Nicholas E., Mandic, Aleksandra, Omidi, Saeed, Naef, Felix, Suter, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418128/
https://www.ncbi.nlm.nih.gov/pubmed/30872573
http://dx.doi.org/10.1038/s41467-019-09189-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418128/
https://www.ncbi.nlm.nih.gov/pubmed/30872573
http://dx.doi.org/10.1038/s41467-019-09189-8

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