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Combined Tissue-Fluid Proteomics to Unravel Phenotypic Variability in Amyotrophic Lateral Sclerosis

The lack of biomarkers for early diagnosis, clinical stratification and to monitor treatment response has hampered the development of new therapies for amyotrophic lateral sclerosis (ALS), a clinically heterogeneous neurodegenerative disorder with a variable site of disease initiation and rate of pr...

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Detalles Bibliográficos
Autores principales: Leoni, Emanuela, Bremang, Michael, Mitra, Vikram, Zubiri, Irene, Jung, Stephan, Lu, Ching-Hua, Adiutori, Rocco, Lombardi, Vittoria, Russell, Claire, Koncarevic, Sasa, Ward, Malcolm, Pike, Ian, Malaspina, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418138/
https://www.ncbi.nlm.nih.gov/pubmed/30872628
http://dx.doi.org/10.1038/s41598-019-40632-4