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Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination

The elevated level of Steroidogenic Factor 1 (Nr5a1, Sf-1) expression in the male gonadal development pathway, post sex determination, implies a vital role in testis gonadal differentiation. In this study we generated Sertoli cell-specific Nr5a1 KO mice (SC-SF-1(−/−)) at E14.5, which coincides with...

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Detalles Bibliográficos
Autores principales:	Anamthathmakula, Prashanth, Miryala, Chandra Suma Johnson, Moreci, Rebecca S., Kyathanahalli, Chandrashekara, Hassan, Sonia S., Condon, Jennifer C., Jeyasuria, Pancharatnam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418149/ https://www.ncbi.nlm.nih.gov/pubmed/30872705 http://dx.doi.org/10.1038/s41598-019-41051-1

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