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Highly interacting regions of the human genome are enriched with enhancers and bound by DNA repair proteins
In specific cases, chromatin clearly forms long-range loops that place distant regulatory elements in close proximity to transcription start sites, but we have limited understanding of many loops identified by Chromosome Conformation Capture (such as Hi-C) analyses. In efforts to elucidate their cha...
Autores principales: | Sobhy, Haitham, Kumar, Rajendra, Lewerentz, Jacob, Lizana, Ludvig, Stenberg, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418152/ https://www.ncbi.nlm.nih.gov/pubmed/30872630 http://dx.doi.org/10.1038/s41598-019-40770-9 |
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