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Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model
The diverse cellular milieu of the gastric tissue microenvironment plays a critical role in normal tissue homeostasis and tumor development. However, few cell culture model can recapitulate the tissue microenvironment and intercellular signaling in vitro. We used a primary tissue culture system to g...
Autores principales: | Chen, Jiamin, Lau, Billy T., Andor, Noemi, Grimes, Susan M., Handy, Christine, Wood-Bouwens, Christina, Ji, Hanlee P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418230/ https://www.ncbi.nlm.nih.gov/pubmed/30872643 http://dx.doi.org/10.1038/s41598-019-40809-x |
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