The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population

We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significant...

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Detalles Bibliográficos
Autores principales: Sawada, Naoko, Daimon, Masao, Kawata, Takayuki, Nakao, Tomoko, Kimura, Koichi, Nakanishi, Koki, Kurano, Makoto, Hirokawa, Megumi, Xu, Boqing, Yamanaka, Yuko, Kato, Tomoko S., Watanabe, Masafumi, Yatomi, Yutaka, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418254/
https://www.ncbi.nlm.nih.gov/pubmed/30872595
http://dx.doi.org/10.1038/s41598-018-37137-x
Descripción
Sumario:We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significantly associated with impaired diastolic parameters including E/A, E′ and E/E′. Although serum adiponectin levels decreased with increased visceral adiposity, there was no independent association between serum adiponectin levels and diastolic parameters, which suggest that the role of adiponectin in this association might be indirect.

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