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The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population

We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significant...

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Autores principales: Sawada, Naoko, Daimon, Masao, Kawata, Takayuki, Nakao, Tomoko, Kimura, Koichi, Nakanishi, Koki, Kurano, Makoto, Hirokawa, Megumi, Xu, Boqing, Yamanaka, Yuko, Kato, Tomoko S., Watanabe, Masafumi, Yatomi, Yutaka, Komuro, Issei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418254/
https://www.ncbi.nlm.nih.gov/pubmed/30872595
http://dx.doi.org/10.1038/s41598-018-37137-x
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author Sawada, Naoko
Daimon, Masao
Kawata, Takayuki
Nakao, Tomoko
Kimura, Koichi
Nakanishi, Koki
Kurano, Makoto
Hirokawa, Megumi
Xu, Boqing
Yamanaka, Yuko
Kato, Tomoko S.
Watanabe, Masafumi
Yatomi, Yutaka
Komuro, Issei
author_facet Sawada, Naoko
Daimon, Masao
Kawata, Takayuki
Nakao, Tomoko
Kimura, Koichi
Nakanishi, Koki
Kurano, Makoto
Hirokawa, Megumi
Xu, Boqing
Yamanaka, Yuko
Kato, Tomoko S.
Watanabe, Masafumi
Yatomi, Yutaka
Komuro, Issei
author_sort Sawada, Naoko
collection PubMed
description We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significantly associated with impaired diastolic parameters including E/A, E′ and E/E′. Although serum adiponectin levels decreased with increased visceral adiposity, there was no independent association between serum adiponectin levels and diastolic parameters, which suggest that the role of adiponectin in this association might be indirect.
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spelling pubmed-64182542019-03-18 The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population Sawada, Naoko Daimon, Masao Kawata, Takayuki Nakao, Tomoko Kimura, Koichi Nakanishi, Koki Kurano, Makoto Hirokawa, Megumi Xu, Boqing Yamanaka, Yuko Kato, Tomoko S. Watanabe, Masafumi Yatomi, Yutaka Komuro, Issei Sci Rep Article We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significantly associated with impaired diastolic parameters including E/A, E′ and E/E′. Although serum adiponectin levels decreased with increased visceral adiposity, there was no independent association between serum adiponectin levels and diastolic parameters, which suggest that the role of adiponectin in this association might be indirect. Nature Publishing Group UK 2019-03-14 /pmc/articles/PMC6418254/ /pubmed/30872595 http://dx.doi.org/10.1038/s41598-018-37137-x Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sawada, Naoko
Daimon, Masao
Kawata, Takayuki
Nakao, Tomoko
Kimura, Koichi
Nakanishi, Koki
Kurano, Makoto
Hirokawa, Megumi
Xu, Boqing
Yamanaka, Yuko
Kato, Tomoko S.
Watanabe, Masafumi
Yatomi, Yutaka
Komuro, Issei
The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title_full The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title_fullStr The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title_full_unstemmed The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title_short The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
title_sort significance of the effect of visceral adiposity on left ventricular diastolic function in the general population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418254/
https://www.ncbi.nlm.nih.gov/pubmed/30872595
http://dx.doi.org/10.1038/s41598-018-37137-x
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