The Parkinson’s disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4

Mutations within Leucine-rich repeat kinase 2 (LRRK2) are associated with late-onset Parkinson’s disease. The physiological function of LRRK2 and molecular mechanism underlying the pathogenic role of LRRK2 mutations remain uncertain. Here, we investigated the role of LRRK2 in intracellular signal tr...

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Detalles Bibliográficos
Autores principales: Funk, Natalja, Munz, Marita, Ott, Thomas, Brockmann, Kathrin, Wenninger-Weinzierl, Andrea, Kühn, Ralf, Vogt-Weisenhorn, Daniela, Giesert, Florian, Wurst, Wolfgang, Gasser, Thomas, Biskup, Saskia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418296/
https://www.ncbi.nlm.nih.gov/pubmed/30872638
http://dx.doi.org/10.1038/s41598-019-40808-y

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