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Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food

Magnetic molecularly imprinted polymers (MMIPs), combination of outstanding magnetism with specific selective binding capability for target molecules, have proven to be attractive in separation science and bio-applications. Herein, we proposed the core–shell magnetic molecularly imprinted polymers f...

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Autores principales: Liu, Jing-Min, Wei, Shu-Yuan, Liu, Hui-Lin, Fang, Guo-Zhen, Wang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418914/
https://www.ncbi.nlm.nih.gov/pubmed/30965842
http://dx.doi.org/10.3390/polym9100546
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author Liu, Jing-Min
Wei, Shu-Yuan
Liu, Hui-Lin
Fang, Guo-Zhen
Wang, Shuo
author_facet Liu, Jing-Min
Wei, Shu-Yuan
Liu, Hui-Lin
Fang, Guo-Zhen
Wang, Shuo
author_sort Liu, Jing-Min
collection PubMed
description Magnetic molecularly imprinted polymers (MMIPs), combination of outstanding magnetism with specific selective binding capability for target molecules, have proven to be attractive in separation science and bio-applications. Herein, we proposed the core–shell magnetic molecularly imprinted polymers for food analysis, employing the Fe(3)O(4) particles prepared by co-precipitation protocol as the magnetic core and MMIP film onto the silica layer as the recognition and adsorption of target analytes. The obtained MMIPs materials have been fully characterized by scanning electron microscope (SEM), Fourier transform infrared spectrometer (FT-IR), vibrating sample magnetometer (VSM), and re-binding experiments. Under the optimal conditions, the fabricated Fe(3)O(4)@MIPs demonstrated fast adsorption equilibrium, a highly improved imprinting capacity, and excellent specificity to target sterigmatocystin (ST), which have been successfully applied as highly efficient solid-phase extraction materials followed by high-performance liquid chromatography (HPLC) analysis. The MMIP-based solid phase extraction (SPE) method gave linear response in the range of 0.05–5.0 mg·L(−1) with a detection limit of 9.1 µg·L(−1). Finally, the proposed method was used for the selective isolation and enrichment of ST in food samples with recoveries in the range 80.6–88.7% and the relative standard deviation (RSD) <5.6%.
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spelling pubmed-64189142019-04-02 Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food Liu, Jing-Min Wei, Shu-Yuan Liu, Hui-Lin Fang, Guo-Zhen Wang, Shuo Polymers (Basel) Article Magnetic molecularly imprinted polymers (MMIPs), combination of outstanding magnetism with specific selective binding capability for target molecules, have proven to be attractive in separation science and bio-applications. Herein, we proposed the core–shell magnetic molecularly imprinted polymers for food analysis, employing the Fe(3)O(4) particles prepared by co-precipitation protocol as the magnetic core and MMIP film onto the silica layer as the recognition and adsorption of target analytes. The obtained MMIPs materials have been fully characterized by scanning electron microscope (SEM), Fourier transform infrared spectrometer (FT-IR), vibrating sample magnetometer (VSM), and re-binding experiments. Under the optimal conditions, the fabricated Fe(3)O(4)@MIPs demonstrated fast adsorption equilibrium, a highly improved imprinting capacity, and excellent specificity to target sterigmatocystin (ST), which have been successfully applied as highly efficient solid-phase extraction materials followed by high-performance liquid chromatography (HPLC) analysis. The MMIP-based solid phase extraction (SPE) method gave linear response in the range of 0.05–5.0 mg·L(−1) with a detection limit of 9.1 µg·L(−1). Finally, the proposed method was used for the selective isolation and enrichment of ST in food samples with recoveries in the range 80.6–88.7% and the relative standard deviation (RSD) <5.6%. MDPI 2017-10-23 /pmc/articles/PMC6418914/ /pubmed/30965842 http://dx.doi.org/10.3390/polym9100546 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Jing-Min
Wei, Shu-Yuan
Liu, Hui-Lin
Fang, Guo-Zhen
Wang, Shuo
Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title_full Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title_fullStr Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title_full_unstemmed Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title_short Preparation and Evaluation of Core–Shell Magnetic Molecularly Imprinted Polymers for Solid-Phase Extraction and Determination of Sterigmatocystin in Food
title_sort preparation and evaluation of core–shell magnetic molecularly imprinted polymers for solid-phase extraction and determination of sterigmatocystin in food
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418914/
https://www.ncbi.nlm.nih.gov/pubmed/30965842
http://dx.doi.org/10.3390/polym9100546
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