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Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations

For application of polymer nanofibers (e.g., sensors, and scaffolds to study cell behavior) it is important to control the spatial orientation of the fibers. We compare the ability to align and pattern fibers using shear force fiber spinning, i.e. contacting a drop of polymer solution with a rotatin...

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Autores principales: Dotivala, Arzan C., Puthuveetil, Kavya P., Tang, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419197/
https://www.ncbi.nlm.nih.gov/pubmed/30960278
http://dx.doi.org/10.3390/polym11020294
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author Dotivala, Arzan C.
Puthuveetil, Kavya P.
Tang, Christina
author_facet Dotivala, Arzan C.
Puthuveetil, Kavya P.
Tang, Christina
author_sort Dotivala, Arzan C.
collection PubMed
description For application of polymer nanofibers (e.g., sensors, and scaffolds to study cell behavior) it is important to control the spatial orientation of the fibers. We compare the ability to align and pattern fibers using shear force fiber spinning, i.e. contacting a drop of polymer solution with a rotating collector to mechanically draw a fiber, with electrospinning onto a rotating drum. Using polystyrene as a model system, we observe that the fiber spacing using shear force fiber spinning was more uniform than electrospinning with the rotating drum with relative standard deviations of 18% and 39%, respectively. Importantly, the approaches are complementary as the fiber spacing achieved using electrospinning with the rotating drum was ~10 microns while fiber spacing achieved using shear force fiber spinning was ~250 microns. To expand to additional polymer systems, we use polymer entanglement and capillary number. Solution properties that favor large capillary numbers (>50) prevent droplet breakup to facilitate fiber formation. Draw-down ratio was useful for determining appropriate process conditions (flow rate, rotational speed of the collector) to achieve continuous formation of fibers. These rules of thumb for considering the polymer solution properties and process parameters are expected to expand use of this platform for creating hierarchical structures of multiple fiber layers for cell scaffolds and additional applications.
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spelling pubmed-64191972019-04-02 Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations Dotivala, Arzan C. Puthuveetil, Kavya P. Tang, Christina Polymers (Basel) Article For application of polymer nanofibers (e.g., sensors, and scaffolds to study cell behavior) it is important to control the spatial orientation of the fibers. We compare the ability to align and pattern fibers using shear force fiber spinning, i.e. contacting a drop of polymer solution with a rotating collector to mechanically draw a fiber, with electrospinning onto a rotating drum. Using polystyrene as a model system, we observe that the fiber spacing using shear force fiber spinning was more uniform than electrospinning with the rotating drum with relative standard deviations of 18% and 39%, respectively. Importantly, the approaches are complementary as the fiber spacing achieved using electrospinning with the rotating drum was ~10 microns while fiber spacing achieved using shear force fiber spinning was ~250 microns. To expand to additional polymer systems, we use polymer entanglement and capillary number. Solution properties that favor large capillary numbers (>50) prevent droplet breakup to facilitate fiber formation. Draw-down ratio was useful for determining appropriate process conditions (flow rate, rotational speed of the collector) to achieve continuous formation of fibers. These rules of thumb for considering the polymer solution properties and process parameters are expected to expand use of this platform for creating hierarchical structures of multiple fiber layers for cell scaffolds and additional applications. MDPI 2019-02-10 /pmc/articles/PMC6419197/ /pubmed/30960278 http://dx.doi.org/10.3390/polym11020294 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dotivala, Arzan C.
Puthuveetil, Kavya P.
Tang, Christina
Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title_full Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title_fullStr Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title_full_unstemmed Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title_short Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
title_sort shear force fiber spinning: process parameter and polymer solution property considerations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419197/
https://www.ncbi.nlm.nih.gov/pubmed/30960278
http://dx.doi.org/10.3390/polym11020294
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