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Adjustment for treatment changes in epilepsy trials: A comparison of causal methods for time-to-event outcomes
BACKGROUND: When trials are subject to departures from randomised treatment, simple statistical methods that aim to estimate treatment efficacy, such as per protocol or as treated analyses, typically introduce selection bias. More appropriate methods to adjust for departure from randomised treatment...
Autores principales: | Dodd, Susanna, Williamson, Paula, White, Ian R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419234/ https://www.ncbi.nlm.nih.gov/pubmed/29117780 http://dx.doi.org/10.1177/0962280217735560 |
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