Cargando…

Targeted in vivo epigenome editing of H3K27me3

BACKGROUND: Epigenetic modifications have a central role in transcriptional regulation. While several studies using next-generation sequencing have revealed genome-wide associations between epigenetic modifications and transcriptional states, a direct causal relationship at specific genomic loci has...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fukushima, Hiroto S., Takeda, Hiroyuki, Nakamura, Ryohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419334/ https://www.ncbi.nlm.nih.gov/pubmed/30871638 http://dx.doi.org/10.1186/s13072-019-0263-z

Ejemplares similares

Genome-wide analysis of the H3K27me3 epigenome and transcriptome in Brassica rapa
por: Payá-Milans, Miriam, et al.
Publicado: (2019)

H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal Epithelium
por: Kolev, Hannah M., et al.
Publicado: (2022)

Chromatin state analysis of the barley epigenome reveals a higher‐order structure defined by H3K27me1 and H3K27me3 abundance
por: Baker, Katie, et al.
Publicado: (2015)

Investigating crosstalk between H3K27 acetylation and H3K4 trimethylation in CRISPR/dCas-based epigenome editing and gene activation
por: Zhao, Weiye, et al.
Publicado: (2021)

H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks
por: Igolkina, Anna A., et al.
Publicado: (2019)

PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome
por: Meng, Tie-Gang, et al.
Publicado: (2020)

Profiling of H3K4me3 and H3K27me3 and Their Roles in Gene Subfunctionalization in Allotetraploid Cotton
por: Zhang, Aicen, et al.
Publicado: (2021)

Unlinking the methylome pattern from nucleotide sequence, revealed by large-scale in vivo genome engineering and methylome editing in medaka fish
por: Cheung, Napo K. M., et al.
Publicado: (2017)

Stage and Gene Specific Signatures Defined by Histones H3K4me2 and H3K27me3 Accompany Mammalian Retina Maturation In Vivo
por: Popova, Evgenya Y., et al.
Publicado: (2012)

The unfavorable clinical outcome of COVID-19 in smokers is mediated by H3K4me3, H3K9me3 and H3K27me3 histone marks
por: Shirvaliloo, Milad
Publicado: (2022)

Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL
por: Qian, Shuiming, et al.
Publicado: (2018)

Genomic imprinting of Xist by maternal H3K27me3
por: Inoue, Azusa, et al.
Publicado: (2017)

Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin
por: Jamieson, Kirsty, et al.
Publicado: (2016)

Distribution of H3K27me3, H3K9me3, and H3K4me3 along autophagy-related genes highly expressed in starved zebrafish myotubes
por: Biga, Peggy R., et al.
Publicado: (2017)

H3K27me3-H3K4me1 transition at bivalent promoters instructs lineage specification in development
por: Yu, Yue, et al.
Publicado: (2023)

Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC
por: Yang, Hongchun, et al.
Publicado: (2014)

Histone H3K4me3 and H3K27me3 regulatory genes control stable transmission of an epimutation in rice
por: Chen, Xiangsong, et al.
Publicado: (2015)

Integrated analysis and transcript abundance modelling of H3K4me3 and H3K27me3 in developing secondary xylem
por: Hussey, Steven G., et al.
Publicado: (2017)

Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells
por: Zhang, Yanping, et al.
Publicado: (2021)

ChIP-seq profiling of H3K4me3 and H3K27me3 in an invasive insect, Bactrocera dorsalis
por: Zhao, Yan, et al.
Publicado: (2023)

Computational inference of H3K4me3 and H3K27ac domain length
por: Zubek, Julian, et al.
Publicado: (2016)

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
por: Harutyunyan, Ashot S., et al.
Publicado: (2019)

MeCP2 regulates gene expression through recognition of H3K27me3
por: Lee, Wooje, et al.
Publicado: (2020)

Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin
por: He, Chao, et al.
Publicado: (2019)

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX
por: Cuyàs, Elisabet, et al.
Publicado: (2018)

EZH2-Mediated H3K27me3 Targets Transcriptional Circuits of Neuronal Differentiation
por: Buontempo, Serena, et al.
Publicado: (2022)

The H3K27me3 demethylase UTX in normal development and disease
por: Van der Meulen, Joni, et al.
Publicado: (2014)

Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants
por: Crevillén, Pedro
Publicado: (2020)

Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium
por: McErlean, Peter, et al.
Publicado: (2020)

Thermal Manipulation During Embryogenesis Impacts H3K4me3 and H3K27me3 Histone Marks in Chicken Hypothalamus
por: David, Sarah-Anne, et al.
Publicado: (2019)

Coordination of zygotic genome activation entry and exit by H3K4me3 and H3K27me3 in porcine early embryos
por: Bu, Guowei, et al.
Publicado: (2022)

Distinct H3K27me3 and H3K27ac Modifications in Neural Tube Defects Induced by Benzo[a]pyrene
por: Lin, Shanshan, et al.
Publicado: (2023)

CpG islands under selective pressure are enriched with H3K4me3, H3K27ac and H3K36me3 histone modifications
por: Akhtar, Most Mauluda, et al.
Publicado: (2013)

The H3K36me2 writer-reader dependency in H3K27M-DIPG
por: Yu, Jia-Ray, et al.
Publicado: (2021)

In Vivo Identification of H3K9me2/H3K79me3 as an Epigenetic Barrier to Carcinogenesis
por: Piro, Maria Cristina, et al.
Publicado: (2023)

Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3
por: Martins, Nuno M. C., et al.
Publicado: (2016)

Genomic and Gene-Level Distribution of Histone H3 Dimethyl Lysine-27 (H3K27me2) in Arabidopsis
por: Park, Sunchung, et al.
Publicado: (2012)

Targeting H3K27me3 demethylase to inhibit Shh signaling and cholesterol metabolism in medulloblastoma growth
por: Deng, Hongshi, et al.
Publicado: (2022)

Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease
por: Lee, Min Young, et al.
Publicado: (2020)

Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin
por: Wang, Qi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8bam0n8g4e6lvug7fohbc0h0bj