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Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad

Seventy-two canine serum samples were analyzed for post-vaccination serum titers of rabies antibodies. The samples were divided into two groups: Group 1 dogs (n = 36) were imported dogs from the Russian Federation (n = 31) or Romania (n = 5), with a mean serum antibody titer value of 1.54 IU/mL. Gro...

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Autores principales: Kaila, Marianne, Marjoniemi, Jasmine, Nokireki, Tiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419415/
https://www.ncbi.nlm.nih.gov/pubmed/30871641
http://dx.doi.org/10.1186/s13028-019-0450-8
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author Kaila, Marianne
Marjoniemi, Jasmine
Nokireki, Tiina
author_facet Kaila, Marianne
Marjoniemi, Jasmine
Nokireki, Tiina
author_sort Kaila, Marianne
collection PubMed
description Seventy-two canine serum samples were analyzed for post-vaccination serum titers of rabies antibodies. The samples were divided into two groups: Group 1 dogs (n = 36) were imported dogs from the Russian Federation (n = 31) or Romania (n = 5), with a mean serum antibody titer value of 1.54 IU/mL. Group 2 dogs (n = 36) were Finnish dogs vaccinated in Finland, with a mean titer of 4.19 IU/mL. Altogether, 14 (39%) dogs (CI 95% 23–56) were without detectable antibodies (≤ 0.1 IU/mL) in Group 1, whereas in Group 2, all dogs had an antibody titer greater than 0.1 IU/mL. A statistically significant difference was observed between these groups when comparing the proportions of dogs with antibody levels less than or exceeding 0.5 IU/mL. In Group 1, 19 out of the 36 dogs (CI 95% 36–70) had serum titer values < 0.5 IU/mL, while in Group 2, only 2 dogs had serum titer values < 0.5 IU/mL. Despite the small sample size, this raises concern over the imported dogs having insufficient antibody levels required for international travel and implies that these dogs had perhaps not been vaccinated, even though they had documentation of vaccination upon arrival.
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spelling pubmed-64194152019-03-27 Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad Kaila, Marianne Marjoniemi, Jasmine Nokireki, Tiina Acta Vet Scand Brief Communication Seventy-two canine serum samples were analyzed for post-vaccination serum titers of rabies antibodies. The samples were divided into two groups: Group 1 dogs (n = 36) were imported dogs from the Russian Federation (n = 31) or Romania (n = 5), with a mean serum antibody titer value of 1.54 IU/mL. Group 2 dogs (n = 36) were Finnish dogs vaccinated in Finland, with a mean titer of 4.19 IU/mL. Altogether, 14 (39%) dogs (CI 95% 23–56) were without detectable antibodies (≤ 0.1 IU/mL) in Group 1, whereas in Group 2, all dogs had an antibody titer greater than 0.1 IU/mL. A statistically significant difference was observed between these groups when comparing the proportions of dogs with antibody levels less than or exceeding 0.5 IU/mL. In Group 1, 19 out of the 36 dogs (CI 95% 36–70) had serum titer values < 0.5 IU/mL, while in Group 2, only 2 dogs had serum titer values < 0.5 IU/mL. Despite the small sample size, this raises concern over the imported dogs having insufficient antibody levels required for international travel and implies that these dogs had perhaps not been vaccinated, even though they had documentation of vaccination upon arrival. BioMed Central 2019-03-14 /pmc/articles/PMC6419415/ /pubmed/30871641 http://dx.doi.org/10.1186/s13028-019-0450-8 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Brief Communication
Kaila, Marianne
Marjoniemi, Jasmine
Nokireki, Tiina
Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title_full Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title_fullStr Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title_full_unstemmed Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title_short Comparative study of rabies antibody titers of dogs vaccinated in Finland and imported street dogs vaccinated abroad
title_sort comparative study of rabies antibody titers of dogs vaccinated in finland and imported street dogs vaccinated abroad
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419415/
https://www.ncbi.nlm.nih.gov/pubmed/30871641
http://dx.doi.org/10.1186/s13028-019-0450-8
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