Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

BACKGROUND: Breast cancer patient-derived xenograft (BC-PDX) models represent a continuous and reproducible source of circulating tumor cells (CTCs) for studying their role in tumor biology and metastasis. We have previously shown the utility of BC-PDX models in the study of CTCs by immunohistochemi...

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Detalles Bibliográficos
Autores principales: Ramirez, Arturo B., Bhat, Raksha, Sahay, Debashish, De Angelis, Carmine, Thangavel, Hariprasad, Hedayatpour, Sina, Dobrolecki, Lacey E., Nardone, Agostina, Giuliano, Mario, Nagi, Chandandeep, Rimawi, Mothaffar, Osborne, C. Kent, Lewis, Michael T., Stilwell, Jackie L., Kaldjian, Eric P., Schiff, Rachel, Trivedi, Meghana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419430/
https://www.ncbi.nlm.nih.gov/pubmed/30871481
http://dx.doi.org/10.1186/s12885-019-5382-1

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