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In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

OBJECTIVES: Widespread antimicrobial resistance often limits the availability of therapeutic options to only a few last-resort drugs that are themselves challenged by emerging resistance and adverse side effects. Apramycin, an aminoglycoside antibiotic, has a unique chemical structure that evades al...

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Detalles Bibliográficos
Autores principales: Juhas, Mario, Widlake, Emma, Teo, Jeanette, Huseby, Douglas L, Tyrrell, Jonathan M, Polikanov, Yury S, Ercan, Onur, Petersson, Anna, Cao, Sha, Aboklaish, Ali F, Rominski, Anna, Crich, David, Böttger, Erik C, Walsh, Timothy R, Hughes, Diarmaid, Hobbie, Sven N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419615/
https://www.ncbi.nlm.nih.gov/pubmed/30629184
http://dx.doi.org/10.1093/jac/dky546