Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii

OBJECTIVES: The potential for synergy between colistin and fusidic acid in the treatment of MDR Acinetobacter baumannii has recently been shown. The aim of this study was to perform an extensive in vitro characterization of this effect using pharmacokinetic-pharmacodynamic modelling (PKPD) of time–k...

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Detalles Bibliográficos
Autores principales: Phee, Lynette M, Kloprogge, Frank, Morris, Rebecca, Barrett, John, Wareham, David W, Standing, Joseph F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419616/
https://www.ncbi.nlm.nih.gov/pubmed/30624656
http://dx.doi.org/10.1093/jac/dky524

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