Cargando…
Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging
Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...
Autores principales: | Hendel, Kristoffer K., Bagger, Charlotte, Olesen, Uffe H., Janfelt, Christian, Hansen, Steen H., Haedersdal, Merete, Lerche, Catharina M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419659/ https://www.ncbi.nlm.nih.gov/pubmed/30859849 http://dx.doi.org/10.1080/10717544.2019.1574937 |
Ejemplares similares
-
Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging
por: Hendel, Kristoffer, et al.
Publicado: (2021) -
Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration
por: Traberg, Andreas, et al.
Publicado: (2022) -
Repeated exposure to fractional CO(2) laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line‐field confocal optical coherence tomography and histology
por: Olesen, Uffe H., et al.
Publicado: (2022) -
Anti-PD-1 Therapy with Adjuvant Ablative Fractional Laser Improves Anti-Tumor Response in Basal Cell Carcinomas
por: Olesen, Uffe Høgh, et al.
Publicado: (2021) -
Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin
por: Wenande, Emily, et al.
Publicado: (2018)