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Novel ophthalmic formulation of myriocin: implications in retinitis pigmentosa
Myriocin is an antibiotic derived from Mycelia sterilia, and is a potent inhibitor of serine palmitoyltransferase, the enzyme involved in the first step of sphingosine synthesis. Myriocin, inhibiting ceramide synthesis, has a great potential for treatment of diseases characterized by high ceramide l...
Autores principales: | Platania, Chiara Bianca Maria, Dei Cas, Michele, Cianciolo, Simona, Fidilio, Annamaria, Lazzara, Francesca, Paroni, Rita, Pignatello, Rosario, Strettoi, Enrica, Ghidoni, Riccardo, Drago, Filippo, Bucolo, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419690/ https://www.ncbi.nlm.nih.gov/pubmed/30883241 http://dx.doi.org/10.1080/10717544.2019.1574936 |
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