Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors

BACKGROUND: Cancer progression is influenced by a pro-tumorigenic microenvironment. The aberrant tumor stroma with increased collagen deposition, contractile fibroblasts and dysfunctional vessels has a major impact on the interstitial fluid pressure (PIF) in most solid tumors. An increased tumor PIF...

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Detalles Bibliográficos
Autores principales: Smeland, Hilde Ytre-Hauge, Lu, Ning, Karlsen, Tine V., Salvesen, Gerd, Reed, Rolf K., Stuhr, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419843/
https://www.ncbi.nlm.nih.gov/pubmed/30876468
http://dx.doi.org/10.1186/s12885-019-5449-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419843/
https://www.ncbi.nlm.nih.gov/pubmed/30876468
http://dx.doi.org/10.1186/s12885-019-5449-z

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