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MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians

MOTIVATION: The volume and complexity of biological data increases rapidly. Many clinical professionals and biomedical researchers without a bioinformatics background are generating big ’-omics’ data, but do not always have the tools to manage, process or publicly share these data. RESULTS: Here we...

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Autores principales: van der Velde, K Joeri, Imhann, Floris, Charbon, Bart, Pang, Chao, van Enckevort, David, Slofstra, Mariska, Barbieri, Ruggero, Alberts, Rudi, Hendriksen, Dennis, Kelpin, Fleur, de Haan, Mark, de Boer, Tommy, Haakma, Sido, Stroomberg, Connor, Scholtens, Salome, van de Geijn, Gert-Jan, Festen, Eleonora A M, Weersma, Rinse K, Swertz, Morris A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419911/
https://www.ncbi.nlm.nih.gov/pubmed/30165396
http://dx.doi.org/10.1093/bioinformatics/bty742
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author van der Velde, K Joeri
Imhann, Floris
Charbon, Bart
Pang, Chao
van Enckevort, David
Slofstra, Mariska
Barbieri, Ruggero
Alberts, Rudi
Hendriksen, Dennis
Kelpin, Fleur
de Haan, Mark
de Boer, Tommy
Haakma, Sido
Stroomberg, Connor
Scholtens, Salome
van de Geijn, Gert-Jan
Festen, Eleonora A M
Weersma, Rinse K
Swertz, Morris A
author_facet van der Velde, K Joeri
Imhann, Floris
Charbon, Bart
Pang, Chao
van Enckevort, David
Slofstra, Mariska
Barbieri, Ruggero
Alberts, Rudi
Hendriksen, Dennis
Kelpin, Fleur
de Haan, Mark
de Boer, Tommy
Haakma, Sido
Stroomberg, Connor
Scholtens, Salome
van de Geijn, Gert-Jan
Festen, Eleonora A M
Weersma, Rinse K
Swertz, Morris A
author_sort van der Velde, K Joeri
collection PubMed
description MOTIVATION: The volume and complexity of biological data increases rapidly. Many clinical professionals and biomedical researchers without a bioinformatics background are generating big ’-omics’ data, but do not always have the tools to manage, process or publicly share these data. RESULTS: Here we present MOLGENIS Research, an open-source web-application to collect, manage, analyze, visualize and share large and complex biomedical datasets, without the need for advanced bioinformatics skills. AVAILABILITY AND IMPLEMENTATION: MOLGENIS Research is freely available (open source software). It can be installed from source code (see http://github.com/molgenis), downloaded as a precompiled WAR file (for your own server), setup inside a Docker container (see http://molgenis.github.io), or requested as a Software-as-a-Service subscription. For a public demo instance and complete installation instructions see http://molgenis.org/research.
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spelling pubmed-64199112019-03-20 MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians van der Velde, K Joeri Imhann, Floris Charbon, Bart Pang, Chao van Enckevort, David Slofstra, Mariska Barbieri, Ruggero Alberts, Rudi Hendriksen, Dennis Kelpin, Fleur de Haan, Mark de Boer, Tommy Haakma, Sido Stroomberg, Connor Scholtens, Salome van de Geijn, Gert-Jan Festen, Eleonora A M Weersma, Rinse K Swertz, Morris A Bioinformatics Applications Notes MOTIVATION: The volume and complexity of biological data increases rapidly. Many clinical professionals and biomedical researchers without a bioinformatics background are generating big ’-omics’ data, but do not always have the tools to manage, process or publicly share these data. RESULTS: Here we present MOLGENIS Research, an open-source web-application to collect, manage, analyze, visualize and share large and complex biomedical datasets, without the need for advanced bioinformatics skills. AVAILABILITY AND IMPLEMENTATION: MOLGENIS Research is freely available (open source software). It can be installed from source code (see http://github.com/molgenis), downloaded as a precompiled WAR file (for your own server), setup inside a Docker container (see http://molgenis.github.io), or requested as a Software-as-a-Service subscription. For a public demo instance and complete installation instructions see http://molgenis.org/research. Oxford University Press 2019-03-15 2018-08-26 /pmc/articles/PMC6419911/ /pubmed/30165396 http://dx.doi.org/10.1093/bioinformatics/bty742 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
van der Velde, K Joeri
Imhann, Floris
Charbon, Bart
Pang, Chao
van Enckevort, David
Slofstra, Mariska
Barbieri, Ruggero
Alberts, Rudi
Hendriksen, Dennis
Kelpin, Fleur
de Haan, Mark
de Boer, Tommy
Haakma, Sido
Stroomberg, Connor
Scholtens, Salome
van de Geijn, Gert-Jan
Festen, Eleonora A M
Weersma, Rinse K
Swertz, Morris A
MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title_full MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title_fullStr MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title_full_unstemmed MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title_short MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians
title_sort molgenis research: advanced bioinformatics data software for non-bioinformaticians
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419911/
https://www.ncbi.nlm.nih.gov/pubmed/30165396
http://dx.doi.org/10.1093/bioinformatics/bty742
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