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A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis
Several developmental stages of spermatogenesis are transcriptionally quiescent which presents major challenges associated with the regulation of gene expression. Here we identify that the zygotene to pachytene transition is not only associated with the resumption of transcription but also a wave of...
Autores principales: | Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420129/ https://www.ncbi.nlm.nih.gov/pubmed/30617251 http://dx.doi.org/10.1038/s41422-018-0128-1 |
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