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Nuclear genetic regulation of the human mitochondrial transcriptome

Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable variatio...

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Detalles Bibliográficos
Autores principales: Ali, Aminah T, Boehme, Lena, Carbajosa, Guillermo, Seitan, Vlad C, Small, Kerrin S, Hodgkinson, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420317/
https://www.ncbi.nlm.nih.gov/pubmed/30775970
http://dx.doi.org/10.7554/eLife.41927