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Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis
Metastatic carcinomatosis cirrhosis is a pattern of metastasis in which malignancy infiltrates the liver and provokes hepatic fibrosis. It is an especially rare complication of several malignancies, including breast cancer. We report a case of a 61-year-old woman with lobular carcinoma of the breast...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420322/ https://www.ncbi.nlm.nih.gov/pubmed/30899627 http://dx.doi.org/10.7759/cureus.3876 |
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author | Knouse, Phillip Hancock, Christie Iwaz, Suzanne Kaiser, Pamela |
author_facet | Knouse, Phillip Hancock, Christie Iwaz, Suzanne Kaiser, Pamela |
author_sort | Knouse, Phillip |
collection | PubMed |
description | Metastatic carcinomatosis cirrhosis is a pattern of metastasis in which malignancy infiltrates the liver and provokes hepatic fibrosis. It is an especially rare complication of several malignancies, including breast cancer. We report a case of a 61-year-old woman with lobular carcinoma of the breast who presented with confusion and rising serum tumor markers without evidence of disease recurrence on imaging. She subsequently developed clinical evidence of hepatic dysfunction and a liver biopsy revealed diffuse infiltration of the liver by breast carcinoma with surrounding fibrous tissue deposition, consistent with metastatic carcinomatosis cirrhosis. This case highlights a rare and clinically significant pattern of metastasis and is the first to describe lobular carcinoma of the breast causing metastatic carcinomatosis cirrhosis. |
format | Online Article Text |
id | pubmed-6420322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-64203222019-03-21 Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis Knouse, Phillip Hancock, Christie Iwaz, Suzanne Kaiser, Pamela Cureus Internal Medicine Metastatic carcinomatosis cirrhosis is a pattern of metastasis in which malignancy infiltrates the liver and provokes hepatic fibrosis. It is an especially rare complication of several malignancies, including breast cancer. We report a case of a 61-year-old woman with lobular carcinoma of the breast who presented with confusion and rising serum tumor markers without evidence of disease recurrence on imaging. She subsequently developed clinical evidence of hepatic dysfunction and a liver biopsy revealed diffuse infiltration of the liver by breast carcinoma with surrounding fibrous tissue deposition, consistent with metastatic carcinomatosis cirrhosis. This case highlights a rare and clinically significant pattern of metastasis and is the first to describe lobular carcinoma of the breast causing metastatic carcinomatosis cirrhosis. Cureus 2019-01-13 /pmc/articles/PMC6420322/ /pubmed/30899627 http://dx.doi.org/10.7759/cureus.3876 Text en Copyright © 2019, Knouse et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Knouse, Phillip Hancock, Christie Iwaz, Suzanne Kaiser, Pamela Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title | Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title_full | Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title_fullStr | Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title_full_unstemmed | Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title_short | Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis |
title_sort | metastatic carcinomatosis cirrhosis: a rare pattern of metastasis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420322/ https://www.ncbi.nlm.nih.gov/pubmed/30899627 http://dx.doi.org/10.7759/cureus.3876 |
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